潘 兵，副教授

博士毕业于清华大学医学部/北京协和医学院，获得医学博士学位

通讯方式：E-mail: panbing@bjmu.edu.cn

目前主要从事：（1）脂蛋白、脂质与血管功能研究，脂蛋白研究重点为高密度脂蛋白（ＨＤＬ）生理与病生理功能。（2）血管功能包括心血管，脑血管，以及肿瘤内血管研究，特别是内皮功能研究。通过蛋白质组学与代谢组学技术来研究动脉粥样硬化等疾病中的重要标志物及其功能，包括蛋白质，代谢物，以及细胞外囊泡与外泌体对血管功能影响。（3）结合新材料技术研究在心脑血管功能方面的应用，包括治疗与体外诊断技术的应用与研发。目前已在Clin Cancer Res，Cardiovasc Res，Free Radic Biol Med，Biochim Biophys Acta，Int J Cancer，Redox Biol等国际学术期刊上发表SCI论文近50篇，承担及参与10余项国家自然科学基金、教育部博士点基金、北京市自然基金以及医-X基金等研究课题。

代表论文：

(1)  Li J, Chen Y, Gao J, Chen Y, Zhou C, Lin X, Liu C, Zhao M, Xu Y, Ji L, Jiang Z, Pan B, Zheng L.Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1b.Cardiovasc Res. 2020. 24:cvaa011.(Impact Factor 8.186)

(2)  He D, Zhao M, Wu C, Zhang W, Niu C, Yu B, Jin J, Ji L, Willard B,   Mathew AV, Chen YE, Pennathur S, Yin H, He Y, Pan B*, Zheng L. Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1. Redox Biol. 2018. 15:228-242. (Impact Factor 9.986)

(3)  Dong M, Zhou C, Ji L, Pan B*, Zheng L*. AG1296 enhances plaque stability via inhibiting inflammatory responses and decreasing MMP-2 and MMP-9 expression in ApoE-/- mice. Biochem Biophys Res Commun. 2017. 489(4):426-431. (Impact Factor 2.985)

(4) Tang Y^#, Pan B^#, Zhou X^#, Xiong K, Gao Q, Huang L, Xia Y, Shen M, Yang S, Liu H, Tan T, Ma J, Xu X, Mu Y, Li K. Wip1-dependent modulation of macrophage migration and phagocytosis. Redox Biol. 2017. 13:665-673. (Impact Factor 9.986)

(5) Pan B^#, Kong J^#, Jin J, Kong J, He Y, Dong S, Ji L, Liu D, He D, Kong L, Jin DK, Willard B, Pennathur S, Zheng L. A novel anti-inflammatory mechanism of high density lipoprotein through up-regulating annexin A1 in vascular endothelial cells. Biochim Biophys Acta. 2016.1861(6):501-512. (Impact Factor 4.996)

(6) Pan B^#, Yu B^#, Ren H, Willard B, Pan L, Zu L, Shen X, Ma Y, Li X, Niu C, Kong J, Kang S, Eugene Chen Y, Pennathur S, Zheng L, High density lipoprotein (HDL) nitration and chlorination catalyzed by myeloperoxidase impairs its effects in promoting endothelial repair, Free Radic Biol Med, 2013, 60:272-281 (Impact Factor 6.02)

(7) Pan B^#, Ren H^#, He Y, Lv X, Ma Y, Li J, Huang L, Yu B, Kong J, Niu C, Zhang Y, Sun WB, Zheng L, HDL of Patients with Type 2 Diabetes Mellitus Elevates the Capability of Promoting Breast Cancer Metastasis, Clin Cancer Res, 2012, 18(5):1246-1256. (Impact Factor 10.199)

(8) Bing Pan, Hui Ren, Xiaofeng Lv, Yangyu Zhao, Baoqi Yu, Yubin He, Yijing Ma, Chenguang Niu, Jinge Kong, Fangzhu Yu, Wen-bing Sun, Youyi Zhang, Belinda Willard and Lemin Zheng, Hypochlorite-induced Oxidative Stress Elevates the Capability of HDL in Promoting Breast Cancer Metastasis, Journal of

(9)Pan B^#, Ren H^#, Ma Y, Liu D, Yu B, Ji L, Pan L, Li J, Yang L, Lv X, Shen X, Chen B, Zhang Y, Willard B, He Y, Zheng L, High-density lipoprotein of patients with type 2 diabetes mellitus elevates the capability of promoting migration and invasion of breast cancer cells, Int J Cancer, 2011, 131(1): 70-82 (Impact Factor 7.36)

(10)Bing Pan, Ming-hui Zhao, Zhong Chen, Lu Lu,Yan Wang, Da-wei Shi, Pei-zhen Han, Inhibitory Effects of Resistin-13- peptide on the Proliferation, Adhesion and Invasion of MDA-MB-231 in Human Breast Carcinoma Cells, Endocrine-related Cancer, 2007, 14(4): 1063-1071 (impact factor 5.331)

奖励情况

1. 中华医学科技奖，代谢性血管疾病的发病机制与防治策略，医学科学技术奖，三等奖，201903304P0808

2. 2013年，获得北京大学医学部“‘2012年度优秀人才奖励计划’青年学者奖”

3. 2010年~2012年，三次入选北京大学医学部“专业技术岗位青年人才支持计划”