
潘 兵,副研究员
博士毕业于清华大学医学部/北京协和医学院,获得医学博士学位
研究领域:代谢与血管稳态;脂质代谢与血管功能研究;
个人简介:本人2008年毕业于清华大学医学部北京协和医学院,获得医学博士学位,随后进入北京大学心血管研究所心血管代谢与蛋白质组学研究室,主要从事脂质脂蛋白与血管功能研究。目前已在Cardiovasc Res、Redox biology、BBA、Free Radic Biol Med、ATVB、Gastroenterology、Aging Cell等国际学术期刊上发表SCI论文50余篇,承担及参与10余项国家自然科学基金、教育部博士点基金、北京市自然基金以及医-X基金等研究课题。
代表论文:
1. Zhou C, Lin Z, Cao H, Chen Y, Li J, Zhuang X, Ma D, Ji L, Li W, Xu S, Pan B*, Zheng L*. Anxa1 in smooth muscle cells protects against acute aortic dissection. Cardiovasc Res. 2021. cvab109. doi: 10.1093/cvr/cvab109.
2. Li J, Chen Y, Gao J, Chen Y, Zhou C, Lin X, Liu C, Zhao M, Xu Y, Ji L, Jiang Z, Pan B*, Zheng L*. Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1b. Cardiovasc Res. 2021.117(2): 450-461.
3. He D, Zhao M, Wu C, Zhang W, Niu C, Yu B, Jin J, Ji L, Willard B, Mathew AV, Chen YE, Pennathur S, Yin H, He Y, Pan B*, Zheng L*. Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1. Redox Biol. 2018. 15: 228-242.
4. Dong M, Zhou C, Ji L, Pan B*, Zheng L*. AG1296 enhances plaque stability via inhibiting inflammatory responses and decreasing MMP-2 and MMP-9 expression in ApoE-/- mice. Biochem Biophys Res Commun. 2017. 489(4):426-431.
5. Tang Y, Pan B, Zhou X, Xiong K, Gao Q, Huang L, Xia Y, Shen M, Yang S, Liu H, Tan T, Ma J, Xu X, Mu Y, Li K. Wip1-dependent modulation of macrophage migration and phagocytosis. Redox Biol. 2017. 13:665-673.
6. Ma G, Pan B, Ren S, Guo C, Guo Y, Wei L, Zheng L, Chen B. 15-oxoeicosatetraenoic acid mediates monocyte adhesion to endothelial cell. Lipids Health Dis. 2017. 16(1):137.
7. Pan B, Kong J, Jin J, Kong J, He Y, Dong S, Ji L, Liu D, He D, Kong L, Jin DK, Willard B, Pennathur S, Zheng L. A novel anti-inflammatory mechanism of high density lipoprotein through up-regulating annexin A1 in vascular endothelial cells. Biochim Biophys Acta. 2016.1861(6):501-512.
8. Huang X, He D, Ming J, He Y, Zhou C, Ren H, He X, Wang C, Jin J, Ji L, Willard B, Pan B*, Zheng L*. High-density lipoprotein of patients with breast cancer complicated with type 2 diabetes mellitus promotes cancer cells adhesion to vascular endothelium via ICAM-1 and VCAM-1 upregulation. Breast Cancer Res Treat. 2016. 155(3):441-55.
9. Pan B, Yu B, Ren H, Willard B, Pan L, Zu L, Shen X, Ma Y, Li X, Niu C, Kong J, Kang S, Eugene Chen Y, Pennathur S, Zheng L. High-density lipoprotein nitration and chlorination catalyzed by myeloperoxidase impair its effect of promoting endothelial repair. Free radical biology & medicine. 2013. 60: 272-281.
10. Pan B, Ren H, He Y, Lv X, Ma Y, Li J, Huang L, Yu B, Kong J, Niu C, Zhang Y, Sun WB, Zheng L. HDL of patients with type 2 diabetes mellitus elevates the capability of promoting breast cancer metastasis. Clinical cancer research. 2012. 18(5): 1246-1256.