2002-2003年度心血管所发表论文统计表

　　第一单位论文：

　　1.        Zhu X, Lin Y, Zhang J, Fu M, Mao Z, Chen YE. Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells. Cell Mol Life Sci. 2003 Jan;60(1):212-8.

　　2.        Zhang GH, Tan XF, Shen D, Zhao SY, Shi YL, Jin CK, Sun WG, Guo YH, Chen KH, Tang J. Gene expression and antitumor effect following im electroporation delivery of human interferon alpha 2 gene. Acta Pharmacol Sin. 2003 Sep;24(9):891-6. (IF=0.688)

　　3.        Yin F, Li P, Zheng M, Chen L, Xu Q, Chen K, Wang YY, Zhang YY, Han C. Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart. J Biol Chem. 2003 Jun 6;278(23):21070-5. Epub 2003 Mar 28. (IF=6.696)

　　4.        Zhang Q, Shi L, Rui W, Lu M, Zheng Y, Ma D, Gu J. Analysis of genomic and protein features of SARS coronavirus. Applied Immunohistochemistry & molecular Morphology. 11(4):298;2003

　　5.        芮伟,张其鹏,石磊,卢铭.SARS冠状病毒基因组、蛋白质与侵入宿主细胞过程的研究近况[J].中华医学杂志,2003,(11):21-29.

2004年度心血管所发表论文统计表

　　第一单位论文：

　　6.        Shi L, Zhang Q, Rui W, Lu M, Jing X, Shang T, Tang J. BioPD: a web-based information center for bioactive peptides. Regul Pept. 2004 Aug 15;120(1-3):1-3. (IF 2.235)

　　7.        Chen KH, Guo X, Ma D, Guo Y, Li Q, Yang D, Li P, Qiu X, Wen S, Xiao RP, Tang J. Dysregulation of HSG triggers vascular proliferative disorders. Nat Cell Biol. 2004 Sep; 6(9):872-83. Epub 2004 Aug 22. (IF 20.268)

　　8.        Guo YH, Gao W, Li Q, Li PF, Yao PY, Chen K. Tissue inhibitor of metalloproteinases-4 suppresses vascular smooth muscle cell migration and induces cell apoptosis. Life Sci. 2004 Oct 1;75(20):2483-93. (IF 1.944)

　　9.        Zhang AH, Gao S, Fan JL, Huang W, Zhao TQ, Liu G. Increased plasma HDL cholesterol levels and biliary cholesterol excretion in hamster by LCAT overexpression. FEBS Lett. 2004 Jul 16;570(1-3):25-9. (IF 3.609)

　　10.    Zheng M, Hou R, Han Q, Xiao RP. Different regulation of ERK1/2 activation by beta-adrenergic receptor subtypes in adult mouse cardiomyocytes. Heart Lung Circ. 2004 Jun;13(2):179-83.

　　11.    Zhang Q, Lu M, Shi L, Rui W, Zhu X, Chen G, Shang T, Tang J. Cardio: a web-based knowledge resource of genes and proteins related to cardiovascular disease. Int J Cardiol. 2004 Nov;97(2):245-9.

　　12.    Xiao RP, Balke CW. Na+/Ca2+ exchange linking beta2-adrenergic G(i) signaling to heart failure: associated defect of adrenergic contractile support. J Mol Cell Cardiol. 2004 Jan;36(1):7-11.

　　13.    Zheng M, Hou R, Xiao RP. Acidosis-induced p38 MAPK activation and its implication in regulation of cardiac contractility. Acta Pharmacol Sin. 2004 Oct;25(10):1299-305. (IF 0.884)

　　14.    Zheng M, Han QD, Xiao RP. Distinct beta-adrenergic receptor subtype signaling in the heart and their pathophysiological relevance. Sheng Li Xue Bao. 2004 Feb 25;56(1):1-15.

　　15.    Xiao RP, Zhu W, Zheng M, Chakir K, Bond R, Lakatta EG, Cheng H. Subtype-specific β-adrenoceptor signaling pathways in the heart and their potential clinical implications. Trends Pharmacol Sci. 2004 Jul;25(7):358-65. (IF 13.965)

　　16.    李慧,周淑佩,范江霖,刘国庆.应用体细胞基因转移技术建立的遗传性极度高血脂小鼠模型[J].中国实验动物学报,2004,(02):19-21+67.

　　17.    罗大力,王淑一,闫洁,陈春蕾,程和平,肖瑞平,张幼怡,韩启德.α-1肾上腺素受体对大鼠乳鼠心室肌细胞内钙的调节及其病理生理学意义[A].中国病理生理学会.国际心脏研究会中国分会第八届学术会议暨中国病理生理学会心血管专业委员会第十一届学术会议论文摘要集[C].中国病理生理学会:,2004:2491

　　18.    陈莉,田珑. 苦味酸天狼星红显示高血压大鼠 I 型胶原. 解剖学杂志28（增刊）：44；2005.

　　19.    景霞,张其鹏,国强华,卢铭,朱晓华,石磊,芮伟,尚彤.网上免费医学生物学数据库指南的建立[J].北京大学学报(医学版),2004,(03):322-326.

　　非第一单位论文：

　　1.      Leblais V, Jo SH, Chakir K, Maltsev V, Zheng M, Crow MT, Wang W, Lakatta EG, Xiao RP. Phosphatidylinositol 3-Kinase offsets cAMP-Mediated Positive Inotropic Effect via Inhibiting Ca2+ Influx in Cardiomyocytes. Circ Res. 2004 Dec 10;95(12):1183-90. Epub 2004 Nov 11. (IF 10.117)

　　2.      Koike T, Liang J, Wang X, Ichikawa T, Shiomi M, Liu G, Sun H, Kitajima S, Morimoto M, Watanabe T, Yamada N, Fan J.Overexpression of Lipoprotein Lipase in Transgenic Watanabe Heritable Hyperlipidemic Rabbits Improves Hyperlipidemia and Obesity. J Biol Chem. 2004 Feb 27;279(9):7521-9. Epub 2003 Dec 3.  (IF 6.482)

　　3.      谭晓红,程萱,毛春明,陈光慧,杨晓.利用基因诱捕技术进行小鼠基因剔除的初步研究[J].生物化学与生物物理进展,2004,(07):606-610. (IF 0.241)

2005年度心血管所发表论文统计表

　　第一单位论文：

　　1.        Luo D, Sun H, Xiao RP, Han Q. Caffeine induced Ca2+ release and capacitative Ca2+ entry in human embryonic kidney (HEK293) cells. Eur J Pharmacol. 2005;509(2-3):109-15. (IF2.432)

　　2.        Luo D, Sun H, Lan X, Xiao R, Han Q. Direct coupling between arachidonic acid-induced Ca2+ release and Ca2+ entry in HEK293 cells. Prostaglandins Other Lipid Mediat. 2005 Jan;75(1-4):141-51.  (IF3.588)

　　3.        Zheng M, Zhu W, Han Q, Xiao RP. Emerging concepts and therapeutic implications of beta-adrenergic receptor subtype signaling. Pharmacol Ther. 2005 Dec;108(3): 257-68. Epub 2005 Jun 24.

　　4.        Zheng M, Reynolds C, Jo SH, Wersto R, Han Q, Xiao RP. Intracellular acidosis-activated p38 MAPK signaling and its essential role in cardiomyocyte hypoxic injury. FASEB J. 2005 Jan;19(1):109-11. Epub 2004 Oct 15.

　　5.        石向东; 李志梁; 吴宏超; 吕永恒; 王同汉; 傅强; 徐春生; 唐朝枢. 尾加压素II促血管内皮细胞分泌肾上腺髓质素的作用. 中华心血管病杂志. 33（9）：836；2005.

　　6.        徐春生,李志梁,严全能,薛世荣,史向东,吴宏超,唐朝枢.糖尿病大鼠心钠素水平的动态观察及依那普利的调节作用[J].高血压杂志,2005,(10):642-645.

　　7.        徐春生,李志梁,张桦,严全能,吴宏超,唐朝枢.糖尿病大鼠血浆肾上腺髓质素的动态变化及依那普利的干预效应[J].第一军医大学学报,2005,(09):1149-1151.

　　8.        徐春生,李志梁,薛世荣,傅强,吴宏超,唐朝枢.糖尿病心肌病大鼠血浆肾上腺髓质素水平的变化趋势及其意义[J].广东医学,2005,(07):901-903.

　　9.        段留法,郑秋甫,张丽萍,曾强,范英鲜,唐朝枢.自发性高血压大鼠血管内皮功能不全发生机理实验研究[J].中国康复理论与实践,2005,(06):413-414.

　　10.    张其鹏,孙冬泳,卢铭,覃璞,尚彤.医学生物信息学在心血管研究领域的应用——数据与知识[J].生理科学进展,2005,(02):119-124.

　　11.    汤健,张其鹏.迎接系统医学生物学的新时代[J].中华医学杂志,2005,(06):5-6.

　　12.    张其鹏,卢铭,孙冬泳,覃璞,尚彤.医学中的系统生物学[J]. 中华医学杂志,2005,(19):1363-1366.

　　13.    高松,刘国庆.固醇辅酶A去饱和酶1基因研究进展[J]. 中国动脉硬化杂志,2005,(01):109-112.

　　14.    刘明,赵铁强,冼勋德,高松,范江霖,黄薇,刘国庆.应用RNA干扰技术体外抑制脂蛋白脂肪酶基因的表达[J].中国动脉硬化杂志,2005,(01):45-47.

　　非第一单位论文：

　　1.      Koike T, Liang J, Wang X, Ichikawa T, Shiomi M, Sun H, Watanabe T, Liu G, Fan J. Enhanced aortic atherosclerosis in transgenic Watanabe heritable hyperlipidemic rabbits expressing lipoprotein lipase. Cardiovasc Res. 2005 Feb 1;65(2):524-34.

　　2.      Yan H, Guo Y, Zhang P, Zu L, Dong X, Chen L, Tian J, Fan X, Wang N, Wu X, Gao W. Superior neovascularization and muscle regeneration in ischemic skeletal muscles following VEGF gene transfer by rAAV1 pseudotyped vectors. Biochem Biophys Res Commun. 2005;336(1):287-98.

　　3.      Wang NP, Guo YH, Chien S, Adenovirus-mediated gene transfer of PPAR(alpha) inhibits injury-induced vascular neointima formation. FASEB JOURNAL 19(4): A697; Part 1 Suppl. S, MAR 4 2005.

　　4.      Huang H, Ma C, Yang M, Tang C, Wang H. Adrenomedullin impairs the profibrotic effects of transforming growth factor-beta1 through recruiting Smad6 protein in human renal tubular cells. Cell Physiol Biochem. 2005;15(1-4):117-24.

2006年度心血管所发表论文统计表

　　第一单位论文：

　　1.      Wang J, Xian X, Huang W, Chen L, Wu L, Zhu Y, Fan J, Ross C, Hayden MR, Liu G. Expression of LPL in Endothelial-Intact Artery Results in Lipid Deposition and Vascular Cell Adhesion Molecule-1 Upregulation in Both LPL and ApoE-Deficient Mice（2006）. Arterioscler Thromb Vasc Biol. Oct 12; (IF 7.0)

　　2.      Huang W, Bi N, Zhang X, Wang Y, Chen B, Liu G. Overexpression of apolipoprotein AV in the liver reduces plasma triglyceride and cholesterol but not HDL in ApoE deficient mice (2006). Biochem Biophys Res Commun. Jul 21;346(1):14-8. (IF 3.0)

3.      Zhao T, Guo J, Li H, Huang W, Xian X, Ross CJ, Hayden MR, Wen Z, Liu G. Hemorheological abnormalities in lipoprotein lipase deficient mice with severe hypertriglyceridemia (2006). Biochem Biophys Res Commun. Mar 24; 341(4): 1066-71. (IF 3.0)

4.      Yu XH*, Zhao TQ*, Wang L, Liu ZP, Zhang CM, Chen R, Li L, Liu G, Hu WC. A novel substitution at the translation initiator codon (ATG-->ATC) of the lipoprotein lipase gene is mainly responsible for lipoprotein lipase deficiency in a patient with severe hypertriglyceridemia and recurrent pancreatitis. Biochem Biophys Res Commun. 2006 Mar 3;341(1):82-7. （co-first author）

5.      鲍红梅; 陈莉; 杨菲; 王宇辉; 张晓红; 刘国庆; 脂蛋白脂酶基因缺陷的极度高甘油三酯血症小鼠胰腺炎的研究。中国病理生理杂志 ，2006, 22 (7) : 1277 – 1281.

6.      张鹏, 汪南平. 脂肪因子与代谢综合征. 基础医学与临床, 2006, 26:20-26.

7.      Wang N, Miao H, Li YS, Zhang P, Haga JH, Hu Y, Young A, Yuan S, Nguyen P, Wu CC, Chien S. Shear stress regulation of Kruppel-like factor 2 expression is flow pattern-specific. Biochem Biophys Res Commun. 2006; 341:1244-1251 (IF 3.0)

8.      Gao DF, Niu XL, Hao GH, Peng N, Wei J, Ning N, Wang N. Rosiglitazone inhibits angiotensin II-induced CTGF expression in vascular smooth muscle cells--Role of PPAR-gamma in vascular fibrosis. Biochem Pharmacol. 2006 Sep 23; [Epub ahead of print] (IF 3.617)

9.      唐植辉，汪南平，钱煦. 血流剪切力在动脉粥样硬化形成中的作用. 生理科学进展 2006 印刷中.

非第一单位论文：

1.      Wu X, Ma J, Han JD, Wang N, Chen YG. Distinct regulation of gene expression in human endothelial cells by TGF-beta and its receptors. Microvasc.Res.2006; 71:12-9 (IF 2.36)

2.      Ball A, Wang J, Wong S, Zielnik B, Mitchell JM, Wang N, Stemerman MB and Mitchell BF. Phorbol ester treatment of human myometrial cells suppresses expression of oxytocin receptor through a mechanism not involving Activator Protein-1. Am J Physiol Endocrinol Metab. 2006 Jun 6; [Epub ahead of print]

3.      Wu C, Li Y, Haga J, Wang N, Lian I, Su F, Usami S and S Chien. Roles of MAP kinases in the regulation of bone matrix gene expressions in human osteoblasts by oscillatory fluid flow. J Cell Biochem. 2006 Jan 26; [Epub ahead of print] (IF 2.946)

4.      Dai J, Li W, Chang L, Zhang Z, Tang C, Wang N, Zhu Y, Wang X. Role of redox factor-1 in hyperhomocysteinemia-accelerated atherosclerosis. Free Radic Biol Med. 2006 Nov 15; 41:1566-1577. Epub 2006 Aug 30. (IF 4.971)

5.      Chen M, Li W, Wang N, Zhu Y, Wang X. ROS and NF-{kappa}B but not LXR Mediate IL-1{beta} Signaling for the Downregulation of ATP-Binding Cassette Transporter A1. Am J Physiol Cell Physiol. 2006 Nov, [Epub ahead of print]

2007年度心血管所发表论文统计表

　　第一单位论文：

1.      Li J, Wang N. Peroxisome proliferator-activated receptor-gamma in vascular biology. Cardiovasc Hematol Disord Drug Targets. 2007;7:109-17.

2.      Gao DF, Niu XL, Hao GH, Peng N, Wei J, Ning N, Wang N. Rosiglitazone inhibits angiotensin II-induced CTGF expression in vascular smooth muscle cells--Role of PPAR-gamma in vascular fibrosis. Biochem Pharmacol. 2007, 73:185-97.

3.      Qin X, Tian J, Zhang P, Fan Y, Chen L, Guan Y, Fu Y, Zhu Y, Chien S, Wang N. Laminar shear stress up-regulates the expression of stearoyl-CoA desaturase-1 in vascular endothelial cells. Cardiovasc Res. 2007; 74:506-14.

4.      Hao G, Niu X, Gao D, Wei J, Wang N. PPAR-gamma ligands suppress angiotensin II-induced plasminogen activator inhibitor-1 and extracellular matrix production in rat cardiac fibroblasts. British J Pharmacol, 2007, in press.

5.      Fan Y, Wang Y, Zhang H, Qin X, Zhu Y, Guan Y, Wang X, Staels B, Chien S, Wang N. Suppression of Pro-inflammatory Adhesion Molecules by PPAR-delta in Human Vascular Endothelial Cells. Arterioscler Thromb Vasc Biol. 2007; Nov, Epub ahead of print.

6.      唐植辉, 汪南平, 钱煦. 血流剪切力在动脉粥样硬化形成中的作用.生理科学进展，2007，1：37-42.

7.      张鹏，汪南平. 脂联素与心血管疾病. 生理科学进展，2007，2：149-152.

8.      Zhang XH, Qi R, Xian X, Yang F, Blackstein M, Deng X, Fan J, Ross C, Karasinska J, Hayden M, Liu G. Spontaneous Atherosclerosis in Aged Lipoprotein Lipase-Deficient Mice With Severe Hypertriglyceridemia on a Normal Chow Diet (2007). Circ. Res. published online Nov 21, 2007.

非第一单位论文：

1.      Chen M, Li W, Wang N, Zhu Y, Wang X. ROS and NF-kB but not LXR mediate IL-1b signaling for the downregulation of ATP-binding cassette transporter A1. Am J Physiol Cell Physiol. 2007; 292:C1493-501

2.      Ai D, Fu Y, Guo DL, Tanaka H, Wang N, Tang CS, Hammock BD, Shyy JY-J, Zhu Y. Angiotensin II Upregulates Soluble Epoxide Hydrolase in Vascular Endothelium In vitro and In vivo. Proc Natl Acad Sci USA. 2007; 104:9018-9023

3.      Dwarakanath RS, Sahar S, Lanting L, Wang N, Stemerman MB, Batarajan R, Reddy MA. Viral Vector Mediated 12/15-Lipoxygenase Overexpression in Vascular Smooth Muscle Cells Enhances Inflammatory Gene Expression and Migration. J Vasc Res. 2007; 45:132-142

4.      Zhu M, Fu Y, Wang N, Guan Y, Tang CS, Shyy J.Y-J., Zhu Y. Laminar Shear Stress Regulates Liver X Receptor in Vascular Endothelial Cells In vitro and In vivo. Arterio Thromb Vasc Biol. 2007, Dec, Epub ahead of print

2008年度心血管所发表论文统计表

　　第一单位论文：

1.      Fan Y, Wang Y, Zhang H, Qin X, Zhu Y, Guan Y, Wang X, Staels B, Chien S, Wang N. Suppression of Pro-inflammatory Adhesion Molecules by PPAR-in Human Vascular Endothelial Cells. Arterioscler Thromb Vasc Biol. 2008;28:315-2 (7.22)

2.      Hao G, Niu X, Gao D, Wei J, Wang N. PPAR-gamma ligands suppress angiotensin II-induced plasminogen activator inhibitor-1 and extracellular matrix production in rat cardiac fibroblasts. British J Pharmacol, 2008;153:1409-1419.(3.76)

3.      Qin X, Xue XF, Fan Y, Tian J, Guan Y, Wang X, Zhu Y, Wang N. Peroxisome proliferator-activated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice. Hepatology.2008; 48:432-41 [highlighted article with editorial] (10.73)

4.      Zhang H, Li Y, Fan Y, Wu J, Zhao B, Guan Y, Chien S, Wang N. Klotho is a target gene of PPAR-gamma. Kidney International 2008; 74:732-9 [highlighted article with editorial] (4.92)

5.      Tang Z, Wang Y, Fan Y, Zhu Y, Chien S and Wang N. Suppression of c-Cbl Tyrosine Phosphorylation Inhibits Proliferation and Migration of Vascular Smooth Muscle Cells in vitro and Neointima Formation in Balloon-Injured Rat Arteries. Circulation. 2008; 118:764-72. (12.75)

6.      Wang N and Zhu Y. Response to Comments. Hepatology.2008; in press (10.73)

7.      Wang N. PPAR-delta in Vascular Pathophysiology. PPAR Res. 2008; in press（特邀综述）

8.      Zhang P, Wang Y, Fan Y, Tang Z, Wang N. Overexpression of Adiponectin Receptors Potentiates the Anti-inflammatory Action of Subeffective Dose of Globular Adiponectin in Vascular Endothelial Cells. Arterioscler Thromb Vasc Biol. 2008; Nov., Epub ahead of print (7.22) （co-first author）

9.      范艳波，汪南平.PPAR-delta在动脉粥样硬化中的作用。生理科学进展. 2008; 39:251-4（特邀综述）

10.  Zhang XH, Qi R, Xian X, Yang F, Blackstein M, Deng X, Fan J, Ross C, Karasinska J, Hayden M, Liu G. Spontaneous Atherosclerosis in Aged Lipoprotein Lipase–Deficient Mice With Severe Hypertriglyceridemia on a Normal Chow Diet. Circ Res. 2008;102:250-256.（9.8）

11.  Wang YH, Sternfeld L, Yang F, Rodriguez J, Ross C, Hayde M, Carriere F, Liu G, Hofer W and Schulz I. Enhanced susceptibility to pancreatitis in severe hypertriglyceridemic lipoprotein lipasedeficient mice and agonist-like function of pancreatic lipase in pancreatic cells. Gut published online 31 Oct 2008. ( 10.2 )

12.  Liu G, Hayden MR. Letter to the editor. Circ Res. 2008;102:e119.(9.8 )

13.  Gao Y, Gao G, He Y, Liu TL, Qi R. Recent Advances of Dendrimers in Delivery of Genes and Drugs。Mini-Reviews in Medicinal Chemistry, 2008, 8, 889-900 (3.2)

非第一单位论文：

1.      Zhu M, Fu Y, Wang N, Guan Y, Tang CS, Shyy J.Y-J., Zhu Y. Laminar Shear Stress Regulates Liver X Receptor in Vascular Endothelial Cells In vitro and In vivo. Arterio Thromb Vasc Biol. 2008;28:527-33 (7.22)

2.      Li Y, Jiang C, Xu G, Wang N, Zhu Y, Tang C, Wang X. Homocysteine upregulates resistin production from adipocytes in vivo and in vitro. Diabetes. 2008;57:817-27 (8.26)

3.      Zhou Y, Zhang X, Chen L, Wu J, Dang H, Wei M, Fan Y, Zhang Y, Zhu Y, Wang N, Breyer M, Guan Y. Expression profiling of hepatic genes associated with lipid metabolism in nephrotic rats. Am J Physiol Renal Physiol.2008; July, Epub ahead of print. (4.4)

2009年度心血管所发表论文统计表

　　第一单位论文：

　　1.      Qi R, Gao Y, Liu T, He R, Tang Y, He Y, Sun S, Li B, Li Y and Liu G. PEG-conjugated PAMAM dendrimers mediate efficient intramuscular gene expression. AAPS J. 2009 Sep;11(3):395-405. (IF 5.2)

　　2.      Xian X, Liu T, Yu J, Wang Y, Miao Y, Zhang J, Yu Y, Ross C, Karasinska J, Hayden M, Liu G, Chui D. Presynaptic Defects underlying Impaired Learning and Memory Function in Lipoprotein Lipase Deficient Mice. J. Neuroscience. 2009，29(14):4681-5. (IF 7.5)

　　3.      Wang Y, Sternfeld L, Yang F, Rodriguez JA, Ross C, Hayden MR, Carriere F, Liu G, Hofer W and Schulz I. Enhanced susceptibility to pancreatitis in severe hypertriglyceridemic lipoprotein lipase deficient mice and agonist-like function of pancreatic lipase in pancreatic cells.Gut.2009;58(3):422-30 (IF =10.2).

　　4.      Xian X, Ding Y, Zhang L, Wang Y, McNutt M, Ross C, Hayden M, Deng X, Liu G. LPL deficiency promotes neointimal formation after oxidative arterial wall injury in ApoE-deficient mice. BBRC 2009:385:563-9 (IF 2.9)

　　5.      Xian X, Ma Y, Yang DD, Huang W, Wang Y, Mueller O, Chang E, Konigshofer Y, Van-Cleve M, Yang J and Liu G. Reduced HDL2b in non-obese type 2 diabetic patients analyzed by a microfluidic chip method in a case-control study. Biomarkers. 2009 Accepted

非第一单位论文：

　　1.      Ma Y, Zhao L, Xian X, Yang D, Huang W, Wang Y, Mueller O, Chang E, Konigshofer Y, Van-Cleve M, Liu G, Yang J. A case-control study on the relationship between the HDL2b and nonacoholic fatty liver disease in Chinese type 2 diabetic patients. Clin Chem Lab Med. 2009;47:1067-72.

　　2.      Zheng J, Tang L, Xian X, Zhou S, Shi H, Jiang Y, Gu Y, Liu G and Tu P. Inhibitory Effect of Triterpenoid Saponins from the Leaves of Ilex kudingcha on Aggregated LDL-Induced Lipid Deposition in Macrophages. Planta Med. 2009;75:1410-4.

　　3.      Ding Y, Wang Y, Huang W, Liu G, Ross C, Hayden MR, Yang J. Glucose intolerance and decreased early insulin response in mice with severe hypertriglyceridemia. Exp. Biol. Med. 2009 accepted

　　4.      Yang F, Wang Y, Sternfeld L, Rodriguez JA, Ross C, Hayden MR, Carriere F, Liu G and Schulz I. The role of free fatty acids, pancreatic lipase and Ca2+ signalling in injury of isolated acinar cells and pancreatitis model in lipoprotein lipase-deficient mice    Acta Physiol. 2009;195:13－28.

2010年度心血管所发表论文统计表

　　第一单位论文：

　　1.    Qin X, Wang X, Wang Y, Tang Z, Cui Q, Xi J, Li YS, Chien S, Wang N. MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells. Proc Natl Acad Sci U S A. 2010;107(7):3240-3244. (IF9.432 )

　　2.    Tian J, Wong WT, Tian XY, Zhang P, Huang Y, Wang N. Rosiglitazone Attenuates Endothelin-1–Induced Vasoconstriction by Upregulating Endothelial Expression of Endothelin B Receptor. Hypertension. 2010;56;129-135. (IF6,614 )

　　3.    Qi R, Mullen DG, Baker JR, Holl MM. The mechanism of polyplex internalization into cells: testing the GM1/caveolin-1 lipid raft mediated endocytosis pathway. Mol Pharm. 2010 Feb 1;7(1):267-79. (IF5.4 )

　　4.    Gao S, He L, Ding Y and Liu G. Mechanisms underlying different responses of plasma triglyceride to high-fat diets in hamsters and mice: Roles of hepatic MTP and triglyceride secretion. BBRC. 2010 Aug 6;398(4):619-26. (IF2.9 )

　　5.    Ding Y, Wang Y, Zhu H, Fan J, Yu L, Liu G and Liu E. Hypertriglyceridemia and delayed clearance of fat load in transgenic rabbits expressing human apolipoprotein CIII. Transgenic Research. Nov. 2010, accepted.(IF 2.53)

　　6.    白璐,王宇辉,丁银元,崔鑫,唐寅,黄薇,张玲,刘国庆.载脂蛋白CIII转基因小鼠表现明显的高甘油三酯血症.中国病理生理杂志.2010,26(11):2235-2239.

　　7.    Ding Y, Wang Y, Huang W, Liu G, Ross C, Hayden MR, Yang J. Glucose intolerance and decreased early insulin response in mice with severe hypertriglyceridemia. Exp. Biol. Med. 2010，235:40-46 （IF 3.25）

非第一单位论文：

　　1.      Xu G, Li Y, An W, Zhao J, Xiang X, Ding L, Li Z, Guan Y, Wang X, Tang C, Zhu Y, Wang N, Li X, Mulholland M, Zhang W. Regulation of gastric hormones by systemic rapamycin. Peptides 31 (2010) 2185–2192.

　　2.      Wang KC, Garmire LX, Young A, Nguyen P, Trinh A, Subramaniam S, Wang N, Shyy JY, Li YS, Chien S. Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth. Proc Natl Acad Sci U S A. 2010;107(7):3240-3244.

　　3.      Dong LH, Wen JK, Liu G, McNutt MA, Miao SB, Gao R, Zheng B, Zhang H, Han M： Blockade of the Ras-extracellular signal-regulated kinase 1/2 pathway is involved in smooth muscle 22 alpha-mediated suppression of vascular smooth muscle cell proliferation and neointima hyperplasia. Arterioscler Thromb Vasc Biol. 2010; 30(4):683-91 （IF 7.25）

　　4.      Jia L, Ma Y, Liu G, Yu L. Dietary cholesterol reverses resistance to diet-induced weight gain in mice lacking Niemann-Pick C1-Like 1. J Lipid Res. 2010; 51(10):3024-33. (IF 4.33)

2011年度心血管所发表论文统计表

　　第一单位论文：

1.      Ding Y, Zhang L, Wang Y, Huang W, Tang Y, Bai L, Ross CJR, Hayden MR, Liu G. Amelioration of Hypertriglyceridemia with Hypo-alpha-cholesterolemia in LPL Deficient Mice by Hematopoietic Cell-Derived LPL. PLos One, 2011, 6(9):e25620.（IF=4.4）

2.      Cui X, Wang Y, Tang Y, Liu Y, Zhao L, Deng J, Xu G, Peng X, Ju S, Liu G and Yang H.Seipin ablation in mice results in severe generalized lipodystrophy. Human Molecular Genetics, 2011,20(15):3022-30.（IF=8.0）

3.      Ding Y, Wang Y, Zhu H, Fan J, Yu L, Liu G and Liu E. Hypertriglyceridemia and delayed clearance of fat load in transgenic rabbits expressing human apolipoprotein CIII. Transgenic Research. 2011,20(4):867-75（IF=2.3）

4.      Liu D, Ji L, Zhang D, Tong X, Pan B, Liu P, Zhang Y, Huang Y, Su J, Willard B, and Zheng L. Nonenzymatic glycation of HDL impairs its anti-inflammatory effects in innate immunity. Diabetes/Metabolism, Research & Review. 2011 Aug.（IF=3.1）

5.      Pan B, Ren H, Ma Y, Liu D, Yu B, Ji L, Pan L, Li J, Yang L, Lv X, Shen X, Chen B, Zhang Y, Willard B, He Y, Zheng L. HDL of Patients with Type 2 Diabetes Mellitus Elevates the Capability of Promoting Migration and Invasion of Breast Cancer Cells. Int J Cancer. 2011 Jul 29.（IF=4.93）

6.      Liu D, Ji L, Tong X, Pan B, Han J, Huang Y, Chen Y, Pennathur S, Zhang Y, and Zheng L. Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1. American Journal of Physiology - Cell Physiology. 2011 Aug.（IF=3.82）

7.      Wang NP, Yin RY, Liu Y, Mao GM, Xi F. Role of Peroxisome Proliferator-Activated Receptor-γ in Atherosclerosis. Circ J 2011; 75: 528 – 535（IF=3.225）

8.      Wang Y, Zhao B, Zhang Y, Tang Z, Shen Q, Zhang Y, Zhang W, Du J, Chien S, Wang N. Krüppel-like Factor 4 is Induced by Rapamycin and Mediates the Anti-proliferative Effect of Rapamycin in Balloon-injured Rat Carotid Arteries. Br J Pharmacol. 2011 Oct 20. （IF=4.925）

9.  张化宇,唐寅,常青,刘璐,王宇辉,蒋孟茜,韩迎春,祁荣,刘国庆. 小鼠对雨蛙肽诱发急性胰腺炎易感性的品系差异. 中国病理生理杂志, 2011, 27(11): 2170-2174.

非第一单位论文：

1.      Wei J, Ouyang H, Wang Y, Pang D, Cong XN, Wang T, Leng B, Li D, Li X, Wu R, Gao F, Deng Y, Liu B, Li Z, Lai L, Feng H, Liu G, Deng X. Characterization of A Hypertriglyceridemic Transgenic Miniature swine Model expressing Human Apolipoprotein CIII. FEBS J 2011 Oct. Epub ahead of print （IF=2.7）

2.      Hu G, Zhao Y, Tang Y, Wang Y, Liu L, Li H, Liu Y, Cui X, Yu Y, Guo C, Wang X, Liu G. Development of A Novel Model of Hypertriglyceridemic Acute Pancreatitis in Hamster: Protective Effects of Probucol. Pancreas, Oct. 2011, Accepted（IF=2.2）

3.      Peng X, Ju S, Qin Y, Fang F, Cui X, Liu G, Ni Y, Teng G. Quantification of Liver Fat in Mice: Comparing Dual-Echo Dixon Imaging, Chemical Shift Imaging and 1H-MR Spectroscopy.  J Lipid Res. 2011, Epub ahead of print（IF=6.2）

4.      Wang Y, Tong J, Li S, Zhang R, Chen L, Zheng M, Wang M, Wang Y, Liu G, Dai D, Zhao Y, Li N: Over-expression of Human Lipoprotein Lipase in Mouse Mammary Glands Leads to Reduction of Milk Triglyceride and Delayed Growth of Suckling Pups. PLos One. May, 2011, Epub ahead of print（IF=4.2）

5.      Zhang T, Yao S, Wang P, Yin C, Xiao C, Qian M, Liu D, Zheng L, Meng W, Zhu H, Liu J, Xu H, Mo X. APOA-II DIRECTS MORPHOGENETIC MOVEMENTS OF ZEBRAFISH EMBRYO BY PREVENTING CHROMOSOME FUSION DURING NUCLEAR DIVISION IN YOLK SYNCYTIAL LAYER. the Journal of Biological Chemistry. 2011 Jan 6. （IF=5.33）

6.      郭静，郑乐民，邱锦云，任小平，牛晨光，冯方波. 精神分裂症循环免疫复合物Mr 187000蛋白质组分的鉴定及意义.免疫学杂志2011年07期.

2012年心血管所发表论文统计