此次研讨会由我心血管研究所与澳大利亚Baker IDI心脏与糖尿病研究所的40余名知名专家教授，就心脏与糖尿病领域的研究热点进行学术交流, 热忱欢迎老师与同学们光临

地点：北京大学医学部 逸夫楼二层大会议厅

时间：2008年9月24日 09：00－18：00

Scientific Program

　　09:00-09:20 WELCOME

　　09:20-10:40 SESSION 1:

　　                    Heart Failure and Risk Factors: Clinical Research

　　                    Chaired by Youfei Guan and Markus Schlaich

　　09:20     Markus Schlaich

　　              Resistant Hypertension

　　09:40     Murray Esler

　　              Neural Mechanisms of Psychogenic Heart Disease

　　10:00     Yong Huo

　　               Re-evaluating the role of homocysteine and folic acid in cardiovascular disease

　　10:20     Melinda Carrington

　　              What are the likely contributors to a future epidemic of heart failure in China?

　　10:40-11:00    Morning tea break

　　11:00-12:20    SESSION 2:

　　                        Novel Research Findings and Techniques

　　                        Chaired by Dmitri Sviridov and Qinghua Cui

　　11:00   Assam El-Osta

　　            Transient hyperglycemia induces vascular epigenetic changes that cause persistent increased gene expression during subsequent normoglycemia

　　11:20   Qinghua Cui

　　            Predicting the co-expression pattern of human intronic microRNAs and their host genes based on machine learning

　　11:40    Peter Meikle

　　             The role of lipidomics in the diagnosis, prognosis and monitoring of cardiovascular disease

　　12:00    Karlheinz Peter

　　             History and perspective on anti-platelet therapy

　　12:20-14:00    Lunch and Poster Session

　　13:00-14:00    SESSION 3:

　　                       Poster viewing and free discussion

　　                       List of poster presentations:

　　Peter Little： Smad and p38 MAP kinase-mediated signalling of proteoglycan synthesis in vascular smooth muscle.

　　Peter Meikle： Plasma lipid profiling: Identification of unstable coronary artery disease

　　Julie McMullen： Phosphoinositide 3-kinase (p110alpha) protects the heart against cardiac dysfunction,fibrosis and atrial fibrillation.

　　Xiao-Jun Du： Regional and systemic inflammatory responses fol owing acute myocardial infarction

　　Dmitri Sviridov： Lipoproteins and Atherosclerosis

　　Karin Jandeleit-Dahm： The role of the AGE/RAGE pathway in diabetes accelerated atherosclerosis and heart disease

　　Geoff Head, T Nguyen-Huu, L LaGreca, A Shweta: Neural control of blood pressure and cardiovascular reactivity to stress in a spontaneously hypertensive mouse

　　Geoff Head： Novel measure of the power of the morning blood pressure surge from ambulatory blood pressure recordings

　　Rebecca Ritchie： Nitroxyl (HNO) is a novel anti-hypertrophic mediator in neonatal cardiomyocytes: Role of cGMP-dependent antioxidant actions

　　Rebecca Ritchie： Type 2 diabetic cardiomyopathy in db/db mice is characterised by progressive fibrosis, myocyte hypertrophy and oxidative stress

　　Zemin Cao： Angiotensin II receptors and vascular injury

　　Terri Allen： Role of rennin angiotensin system in diabetic atherosclerosis

　　Zhonglin Cai： Modulation of TGF-β/Smad signaling by Cell Division Autoantigen 1 (CDA1), Implication in diabetic atherosclerosis and nephropathy

　　Liling Wu： Globular Adiponectin Inhibits Angiotensin II-Induced Nuclear FactorκB Activation through AMP-Activated Protein Kinase in Cardiac Hypertrophy

　　Nanping Wang： Anti-inflammatory roles of Adiponectin Receptors in Vascular

　　Endothelial Cells

　　Yi Zhu： Angiotensin II-induced Cardiac Hypertrophy – The Role of Soluble

　　Epoxide Hydrolase

　　Leming Zheng： Proteomic Study of Cardiovascular Diseases

　　Cui Qinghua： An analysis of human microRNA and disease associations

　　Yuansheng Gao： Role of MYPT1 in reduced PKG actions of nitrate tolerant in coronary arteries

　　Guoqing Liu： Severe Hypertriglyceridemia and Multi-organ Injury

　　Wei Gao： Biological Effects in Ischemic Skeletal Muscles following VEGF Gene transfer by the New Types of Adeno-associated Virus Serotype 1 Vectors

　　Youyi Zhang： Intermolecular Failure of L-type Ca2+ Channel and Ryanodine Receptor Signaling in Hypertrophy

　　Xian Wang： Homocysteine Promotes Vascular Smooth Muscle Cell Migration through Induction of Adipokine Resistin:Further Evidence of Adipokine-Vascular Interaction

　　Chunyan Zhou： WNT signaling promotes Nkx2.5 expression and early cardiomyogenesis via down-regulation of Hdac1

　　Junbao Du： Hydrogen sulfide, a novel cardiovascular gasotransmitter

　　14:00-15:00    SESSION 4:

　　                       Vascular Biology and Signalling

　　                       Chaired by Yuansheng Gao and Geoff Head

　　14:00     Nanping Wang：Role of PPAR-δin vascular biology

　　14:20     Jaye Chin-Dusting： The functional heterogeneity of the endothelium

　　14:40     Lemin Zheng: Cardiovascular biomarkers

　　15:00-16:20    SESSION 5:

　　                       Metabolic Syndrome and Complications

　　                       Chaired by Peter Little and Xian Wang

　　15:00             Dianna Magliano： Diabetes and CVD: Epidemiological insights

　　15:20    Xian Wang： Hyperhomocysteinemia accelerates pathogenesis of atherosclerosis: role of T lymphocytes

　　15:40    Terri Allen： Diabetes associated atherosclerosis

　　16:00    Youfei Guan: Prostaglandin Receptors and Blood Pressure Regulation

　　16:20-16:40    Afternoon tea break

　　16:40-17:10    SESSION 6:

　　                       Introduction of Institutes

　　                       Chaired by David Lloyd and Nanping Wang

　　16:40    Youyi Zhang

　　             Director, Institute of Cardiovascular Sciences

　　             Peking University Institute of Cardiovascular Sciences &

　　             Key Laboratory of Molecular Cardiovascular Sciences,

　　             Ministry of Education

　　17:00    Garry Jennings

　　             Director, Baker IDI Heart and Diabetes Institute

　　             (IDI: International Diabetes Institute)

　　17:20    General Discussion

　　             Looking into collaborations at the Institute Level

　　19:00- Conference dinner